Recruiting the right patients for clinical trials is one of the biggest bottlenecks in drug development. Traditional methods rely on manual database searches, physician referrals, and broad advertising campaigns that are slow, expensive, and often fail to meet diversity or eligibility criteria. Leading Swiss pharma and life sciences companies are now deploying sovereign agentic patientmatching systems that continuously analyse electronic health records, trial criteria, and patient consent data to identify and engage eligible participants in real time — all while keeping every piece of sensitive health data securely on Swiss infrastructure.
- Clinical trial recruitment time reduced by up to 4× compared to traditional methods
- Patient matching accuracy improved dramatically with sovereign RAG over internaldatasets
- Full EU AI Act compliance and patient privacy guaranteed by design
- Sovereign deployment on Exoscale SKS ensures complete data residency
- Clinical operations teams reclaim up to 70% of their time previously spent on manualscreening
The Persistent Challenge of Patient Recruitment in Clinical Trials
Finding and enrolling suitable participants remains the leading cause of trial delays and cost overruns. Manual screening of thousands of records, fragmented data sources, and strict privacy regulations make the process slow and inefficient, often resulting in missed enrolment targets and extended development timelines.
The Sovereign Agentic Patient Matching Solution
A new generation of autonomous multi-agent systems is transforming the process. These sovereign agentic platforms continuously scan de-identified health records, trial protocols, and patient-consent databases to identify perfect matches in real time — all running inside dedicated Swiss tenants on Exoscale SKS.
How the Multi-Agent System Works
Built with LangGraph orchestration, the solution coordinates specialised agents:
• Eligibility Matching Agent – compares trial inclusion/exclusion criteria against patient data using sovereign RAG
• Consent & Privacy Agent – ensures GDPR/DSG and patient consent compliance at every step
• Engagement Orchestration Agent – triggers personalised outreach through approved channels
• Diversity & Compliance Agent – monitors recruitment for demographic balance and regulatory reporting
The entire workflow is fully auditable and remains 100% within Swiss borders.
Proven Results from Swiss Life Sciences Companies
Early deployments have delivered impressive outcomes:
• Recruitment timelines shortened by up to 4×
• Enrolment rates increased by 50–80%
• Screening costs reduced by 40–60%
• Higher diversity in trial populations achieved automatically
• Full EU AI Act compliance with explainable AI decisions
Why Sovereignty Is Essential for Clinical Trial Recruitment
Patient health data is among the most sensitive information in existence. Foreign cloud solutions cannot meet the strict data residency, privacy, and regulatory control requirements that Swiss life sciences companies must satisfy. Sovereign agentic platforms deliver both world-class recruitment speed and full Swiss compliance.
